Introducing Metabolic Beauty
Your skin cells have
an energy problem.
We solved it.
Powered by patented Krebs cycle science — the first skincare line
that restores mitochondrial function from within
in 30 minutes
measurable improvement
skin redness, 4 weeks
Science that works
inside the cell
Most skincare treats the surface. IDEO treats the source. Our patented RMA Complex — Resveratrol, Malate, and layered Antioxidants — delivers Krebs cycle intermediates directly to skin cells, restoring the mitochondrial function that powers cellular repair, renewal, and radiance.
Krebs Cycle Priming
Malate, succinate, and fumarate prime the cycle with four-carbon intermediates — enabling aging cells to resume efficient energy production.
ATP Restoration
A functioning Krebs cycle feeds the electron transport chain, restoring the ATP production that powers cellular repair, division, and collagen synthesis.
Layered Antioxidant Regulation
A ladder of antioxidants from grape skins, green tea, and raw chocolate — each with distinct redox potentials — restores the cell's own ability to regulate free radicals.
Visible Transformation
Restored cellular turnover, supported collagen synthesis, and visibly younger-behaving skin.
"Every moisturizer helps your skin look better.
IDEO is the only one designed to help your skin cells work better."
The Metabolic Beauty Difference
How IDEO compares to
what QVC already trusts
Independent instrument-validated studies. True untreated controls. ICH GCP compliance. IDEO's clinical dossier matches the methodology of QVC's most established brands — with a mechanism none of them can claim.
| Brand | Headline Claim | Study Design | N | Mechanism | Evidence |
|---|---|---|---|---|---|
| IDEO SkincareYou are here | 63.58% hydration at 30 min — 100% of subjects | Corneometer · ICH GCP · untreated control | 25–30 | Krebs cycle priming — root cause | |
| Elemis Pro-Collagen | 234% hydration; 100% fine line reduction | Instrument · baseline comparison | 30 | Marine algae — barrier/moisture | |
| Perricone MD Cold Plasma+ | 100% fine line improvement; 97% pore reduction | Image analysis · cutometer | 30 | Vitamin C ester · peptides | |
| Tatcha Longevity Serum | 55% reduction in senescent cell markers | In vitro + 39-subject clinical | 39 | Senescence targeting — in vitro only | |
| Peter Thomas Roth Peptide 21 | 116% hydration immediately; 100% felt plumped | Consumer perception · 1 week | 30 | 21 peptides — surface appearance |
● Evidence score reflects independence, instrument validation, control design, and disclosure. Source: publicly available brand data, March 2026.
Dr. John P. Blass
A neurologist who spent 20 years restoring energy to dying brain cells asked: what would happen if we did the same for skin?
Professor of Neurology & Biochemistry, Weill Cornell Medical College — pioneer in mitochondrial metabolism research
Author of prior U.S. Patent 6,537,969 — applying mitochondrial substrate therapy to Alzheimer's, Parkinson's, and Huntington's diseases
Nobel Prize–nominated for foundational work in cellular energy metabolism
IDEO's formulation is a direct translation of 20 years of neurological research to skin cell biology — U.S. Patent 8,435,547 B2
Two products.
One complete system.
Skin Memory
Daily Moisturizer
Clinically proven to increase skin hydration by 63% in 30 minutes. In a controlled study, 100% of subjects showed measurable improvement — and sustained 43% more hydration for a full 8 hours.
From 20
Shop MoisturizerSkin Memory
Serum
A clinically validated multi-action serum. In an independent Tier-1 lab study, statistically significant improvements across redness, radiance, and skin tone — with visible results in as few as 5 days.
From 5
Shop SerumYour skin cells are
waiting to be refueled.
Join the first generation of women discovering that the most powerful thing you can do for your skin is restore its energy from within.