Skin Longevity Protocol - 12-Month Supply

6 Serums (30 mL) + 6 Moisturizers (50 mL) · A full year of the protocol

$879.75$1,470.00bought separately

A full year of the protocol, about $73.31 a month

Free domestic shipping. Taxes calculated at checkout.

The deepest changes are the ones that hold.

A full year of the complete two-step protocol: six Skin Memory Serums and six Skin Memory Daily Moisturizers. Skin biology changes over time, and the changes that last are built on consistency. A year of R·M·A Complex™ gives your cells not just the signal to renew, but the steady conditions to keep doing it. Results build, month after month. This is the full commitment, at the lowest price per day we offer. No retinol, no irritation, no adjustment period.

  • Visible results from day 5
  • 35% faster cell renewal at 4 weeks
  • Our lowest price per day
  • Enough for two people for six months
  • Try the first set for 60 days. Not for you? Return the unopened bottles for a full refund.
  • Your protocol price is locked for your next order, even if our prices rise.
What it does

A naturally firmer, lifted look

Smoother texture and a radiant glow

More even-looking tone, less visible redness

All-day hydration, clinically proven

A calmer, more resilient skin barrier

Key ingredients

R·M·A Complex™, in both steps

Niacinamide + vitamin C

Ergothioneine

Bakuchiol, in the Moisturizer

Hyaluronic acid, in both steps

Squalane + shea butter, in the Moisturizer

Full ingredient lists

Skin Memory Serum: DISTILLED WATER (AQUA), DIETHYLHEXYL MALEATE, SODIUM HYALURONATE SLMW, NIACINAMIDE (VITAMIN B3), POLYSORBATE 20, ETHYL ALCOHOL 200 PROOF, PEG-60 HYDROGENATED CASTOR OIL, SODIUM HYALURONATE, SORBITAN LAURATE POLYGLYCERYL-4 LAURATE DILAURYL CITRATE, SODIUM ACRYLATE / SODIUM ACRYLOYLDIMETHYL TAURATE COPOLYMER ISOHEXADECANE POLYSORBATE 80, PHENOXYETHANOL, ALOE BARBADENSIS LEAF POWDER, TETRAHEXYLDECYL ASCORBATE (VITAMIN C), ERGOTHIONEINE, POLYSORBATE 80, SODIUM BENZOATE, HYDROGENATED ETHYLHEXYL OLIVATE (AND) HYDROGENATED OLIVE OIL UNSAPONIFIABLES, RESVERATROL POWDER

Skin Memory Daily Moisturizer: WATER (AQUA), DIMETHICONE, GLYCERIN, DIETHYLHEXYL MALEATE, NIACINAMIDE, ETHYLHEXYL OLIVATE, SQUALANE, COCO-CAPRYLATE/CAPRATE, BUTYROSPERMUM PARKII (SHEA) BUTTER, TRIHEPTANOIN, POLYGLYCERYL-4 CAPRATE, SODIUM STEAROYL GLUTAMATE, SCLEROCARYA BIRREA SEED OIL, BAKUCHIOL, TETRAHEXYLDECYL ASCORBATE (VITAMIN C), GLUTAMIC ACID, LYSINE HCL, THREONINE, ARGININE, HYDROLYZED SODIUM HYALURONATE, SODIUM HYALURONATE, GLYCINE SOJA (SOYBEAN) EXTRACT TOCOPHEROL, PHENOXYETHANOL, BETAINE, GLYCINE SOJA (SOYBEAN) OIL, COLLAGEN AMINO ACIDS, HAEMATOCOCCUS PLUVIALIS EXTRACT, PHOSPHOLIPIDS, SODIUM PHYTATE, SODIUM PCA, SODIUM LACTATE, MANNITOL, ERGOTHIONEINE, BIOTIN (VITAMIN B7), PCA, POLYGLUTAMIC ACID, LEUCONOSTOC/RADISH ROOT FERMENT FILTRATE, SODIUM ACETYLATED HYALURONATE, SERINE, ALANINE, GLYCINE, SODIUM HYALURONATE CROSSPOLYMER, ACETYL HEXAPEPTIDE-8, PROLINE, DIMETHICONOL, POLYSILICONE-11, C9-12 ALKANE, DILINOLEIC ACID/BUTANEDIOL COPOLYMER, CASTOR OIL/IPDI COPOLYMER, PHENETHYL ALCOHOL, SODIUM POLYACRYLATE, AMMONIUM ACRYLOYLDIMETHYLTAURATE/BEHENETH-25 METHACRYLATE CROSSPOLYMER, 1,2-HEXANEDIOL, ETHYLHEXYLGLYCERIN, PROPANEDIOL, PENTYLENE GLYCOL, POTASSIUM SORBATE, CAPRYLYL GLYCOL

Fragrance-free. Suitable for all skin types, including sensitive skin.

How to use

1. Serum. Shake well. Apply to clean, completely dry face and neck, morning and night, and let it absorb.

2. Moisturizer. Follow right away with an even layer, massaging upward. Layers well under SPF and makeup.

For best results, exfoliate 1 to 3 times a week, before the Serum.

Keep away from contact with eyes.

Shipping & returns

Free domestic shipping on every order. Not in love? Get a full refund within 60 days of delivery, no questions asked.

Two steps. Every day, for a full year.

The same protocol as the Duo, committed to for a full year. Each step does a job the other can't, and a year lets results compound instead of stall.

Refuel.

Skin Memory Serum

A weightless serum that supports the cellular energy skin needs to keep renewing. Firmer-looking, smoother, more even skin, with visible results from day 5.

On clean, completely dry skin, morning and night.

Explore the Serum

Lock it in.

Skin Memory Daily Moisturizer

Hydrates on contact, with a 63% boost in 30 minutes, while strengthening the barrier so the Serum's work stays where it belongs.

Right after the Serum, massaged upward.

Explore the Moisturizer

Why it's built as two.

  1. 1Renewal needs fuel.

    Skin rebuilds itself constantly, and that work runs on cellular energy. The Serum supports the supply.

  2. 2Fuel needs protecting.

    A weak barrier lets moisture escape and slows repair. The Moisturizer hydrates, reinforces the barrier and seals the Serum in.

  3. 3Consistency compounds.

    Collagen and barrier renewal run in cycles of weeks. Morning and night, every day, is how results build and keep building.

Bought separately, $1,470. As a 12-month protocol, $879.75. You save $590.25.

A full year of the protocol costs less than two NAD+ IV sessions.

Start the protocol

As featured in

ForbesThe New York TimesLongevity.TechnologyBeauty MatterFuture of SkincareThe Drew Barrymore Show
IDEO Skin Memory Protocol

A year of compounding results.

Months 1–2

Hydration and radiance

Visible results from day 5. Skin looks plumper, smoother and brighter.

Months 3–4

Faster renewal

Visibly refined pores and a more even surface.

Months 5–6

Firmer, more elastic

Skin looks lifted, with elasticity restored.

Months 7–12

Results that hold

Staying consistent keeps renewal running, so results keep building instead of fading.

Day 5 to 4-week results come from a 4-week clinical study of 30 women. The months after reflect continued, consistent use. Individual results vary.

A full year, for the least per day.

Every option is the same two-step protocol. What changes is how long it lasts, and what you pay for each day of it.

  1. Serum + Moisturizer, bought separately$245.00 · about 8 weeks
    $4.38/day
  2. The Duo$220.00 · about 8 weeks
    $3.93/day10% less
  3. 12-Month Protocol$879.75 · 6 Serums + 6 Moisturizers
    $2.62/day40% less

Cost per day is worked out from current prices and twice-daily use, with each Serum and Moisturizer lasting about 8 weeks.

Results that last.

★★★★★
The serum has been a staple for years and I am told that I look in my late 30s even though I am 15 years older!
Maile A. · Verified buyer, 4 years
★★★★★
I have been using this serum now for almost a year. All I know is that I am asked by my friends what I have done because my skin looks so good.
Margery E., 64 · Verified buyer
★★★★★
I used Isdin for years until my producer told me about Ideo and gifted me a bottle. I have seen amazing results and I am a convert! Not going back.
Sabrina R. · Verified buyer

In their own words.

Visible Performance

  • 97%noticed improvement in skin's appearance
  • 100%said skin looks smoother and softer
  • 93%said skin looked more hydrated
  • 72.4%saw fewer visible fine lines and wrinkles in 4 weeks

From separate consumer studies of Skin Memory Serum and Skin Memory Daily Moisturizer. Individual results vary.

Model holding IDEO Skin Memory Serum
TreatmentNAD+ IV TherapyNAD+ InjectionsRadiofrequency MicroneedlingExosome / PRP Microneedling
Cost over 12 months$880$7,800$5,400$2,700$3,000
No clinic or office visit
Visible results in first week
No downtime
Targets cellular energy
Non invasive / no needles

IDEO: a full year of the protocol. Treatments are estimated at typical per-session prices on a conservative schedule: NAD+ IV and NAD+ injections once a month (12 sessions), RF microneedling as a standard 3-session series, exosome/PRP microneedling as a 3-session series plus one maintenance session. Clinic prices and schedules vary.

What's working, and where.

One complex runs through both steps. Around it, each formula carries the actives suited to its job.

R·M·A Complex™Cellular energy · both steps

The energy complex born in Dr. Blass's brain research, built around maleate, which primes the cell's energy cycle. It's in both formulas, so the work the Serum starts carries through the Moisturizer.

Niacinamide, vitamin C + ergothioneineTone and defense

Two proven brighteners to even out tone and soften the look of dark spots, with ergothioneine, a rare antioxidant the body has its own transporter for, adding a layer of defense.

BakuchiolRenewal without retinol · Moisturizer

A plant-based alternative to retinol, for smoother-looking skin without the irritation or the adjustment period.

Hyaluronic acid + barrier lipidsHydration and barrier

Two forms of hyaluronic acid in the Serum and four in the Moisturizer, with squalane, shea butter and phospholipids to hold hydration in and keep the barrier calm.

Dr. John P. Blass

From the brain to the skin.

For more than 30 years, Dr. John P. Blass asked one question: how to prevent cells from losing energy as we age? From Harvard to London to Cornell's neurology lab, he searched for the answer in mitochondrial research nominated for a Nobel Prize.

Then his wife, Gitte, had a scar that wouldn't fade. He theorized that because skin and brain emerge from the same embryonic layer of cells, the formula he had developed for cognitive decline might help. He tried it and the scar vanished from 60 year old skin. That became R·M·A Complex™, the innovative heart of both steps of the protocol, and it works like nothing else.